一场生死大战即将展开！加州地区发生里氏9.5级的巨大地震，幸好在普莱斯顿上尉率领下，岛上居民得以存活。然而，此时岛上却陆续发生多起离奇事件；寻弟心切的 麦布莱上尉也在此刻来到岛上，在普莱斯顿上尉调查下发现他们跟拉奇太太凯妮都被抓到南王监狱，并被犯罪团体首领以毒品控制。为了解救无辜的受害居民，普莱斯顿上尉将带领特遣队勇闯魔鬼岛An earthquake measuring 9.5 on the Richter Scale splits California into an island with a perpetual dustcloud hanging over it. The survivors of the terrible ordeal have started to come together in the shape of Nick Preston (Dolph Lundgren) an air force captain, and other fractions of the military, including Sarah McBride and Lucky Simcoe, and have situated themselves in a warfare junkyard, holding weaponry from forgotten conflicts. They are searching for food, fuel and fellow survivors, and a possible path into the next world, while also dodging a violent plague that causes the skin to boil.
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